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There was also a twofold increase in vasodilatory capacity in patients treated with saxagliptin versus placebo, signifying an improvement in the eye vasculature, although the increase was nonsignificant
The isoprostanes: A perspective
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Excess ROS can damage all major cellular constituents (DNA, proteins, and lipids) and even lead to cell death, apoptosis, hypertrophy, fibrosis, and contractile dysfunction in the myocardium [8, 11]
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